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. 2011 Oct 14;6(10):e26289. doi: 10.1371/journal.pone.0026289

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Purcell et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Representative traces illustrate the reduction of calcium-sensitive outward currents following MβCD treatment. I_K(Ca) was defined by subtracting the response to calcium-free from control extracellular solution. (B) Current-voltage (I−V) curves show reduced I_K(Ca) following MβCD treatment (p<0.001, ANOVA). (C) Steady-state I−V curves for K⁺ currents recorded in calcium-free external solution show a comparatively lesser reduction following MβCD treatment (p<0.001, ANOVA).