Figure 5. Cortisone (500 nM, 24 h, black) and cortisol (500 nM, 24 h, dark grey) decrease lipogenesis in differentiated Chub-S7 cells.

The effects of cortisone are blocked by the 11β-hydroxysteroid dehydrogenase inhibitor, PF877423 (5 µM, 24 h, hashed bar). (Data are expressed relative to untreated cells (white bars) and are the mean±se of n = 3–5 experiments, * p<0.05 and † p<0.01).