Table 4.

Conserved domains in surfactant biosynthetic proteins of L. pneumophila

Strain 130b ORF	Gene	Conserved domain in the predicted proteina	E value
lpw_24141	bbcA	Ketoacyl-acyl carrier protein synthase III	2 × 10−39
lpw_24151	bbcB	Acyl-CoA synthetase	5 × 10−120
lpw_24161	bbcC	Acyl-CoA/AMP-acid ligase II	9 × 10−54
lpw_24171	bbcD	None
lpw_24181	bbcE	3-Ketoacyl-acyl carrier protein reductase	4 × 10−30
lpw_24191	bbcF	Ketoacyl-acyl carrier protein synthase III	8 × 10−71
lpw_24131	bbcG	Carboxyltransferase of acetyl-CoA carboxylase	5 × 10−96
lpw_24121	bbcH	Acyl-CoA dehydrogenase	1 × 10−52
lpw_24111	bbcI	GH3 domain	7 × 10−90
lpw_24101	bbcJ	None
lpw_24091	bbcK	None

^aProtein sequences from the 130b genome (http://www.ebi.ac.uk/ena/data/view/FR687201) were analyzed using the conserved domain database at the NCBI. CoA, coenzyme A.