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. 2011 Nov;85(21):11325–11337. doi: 10.1128/JVI.05512-11

Table 2.

Calculated tMRCA values for S and N genes

Genotype and analysis model Strict clock
Relaxed uncorrelated clocka
Log-normal
Exponential
Mean HPD Mean HPD Mean HPD
Constant size
    S gene
    A, B, and C 48.1555 44.7545–53.5444 49.414 44.4431–58.0039 54.284 44.5851–70.9238
    B and C 27.4725 22.2275–33.6636 21.3901 10.6186–33.4467 26.9695 14.7718–42.409
        A 45.5514 44.6245–46.6342 45.62 44.2208–47 46.529 44.3516–50.3417
        B 11.4415 9.5698–13.5421 10.7938 8.2477–14.2259 14.8138 10.0011–21.2453
        C 8.121 7.2977–9.0669 8.2939 7.1553–9.9183 9.2664 7.2557–12.4169
    N gene
        A, B and C 55.6007 44.102–80.1591 55.2781 44.099–79.5748 54.433 44.0908–77.5797
        B and C 26.2353 13.0594–44.625 24.6398 10.2003–43.6165 21.6914 9.1696–40.8566
        A 45.58 44.08–48.971 45.5361 44.08–48.9703 45.5039 44.08–49.1539
        B 16.5939 8.8253–27.7325 15.3999 8.2083–26.293 13.2508 8.1759–22.8651
        C 13.6795 8.2804–21.6243 13.0869 7.6379–21.0773 12.1722 7.4932–20.213
Bayesian skyline
    S gene
        A, B and C 45.0589 44.4048–45.8426 44.982 44.09–46.3717 45.0131 44.1592–46.4873
        B and C 20.8376 17.939–23.7088 10.1779 8.5117–12.5169 10.5825 8.8659–12.8411
        A 44.8137 44.3591–45.3259 44.4406 44.1038–44.9446 44.4342 44.1312–44.8766
        B 9.5314 8.6617–10.4592 8.4944 8.0953–9.0724 8.479 8.1131–9.005
        C 7.3604 7.0823–7.6852 7.3576 7.08–7.8177 7.3233 7.08–7.7445
    N gene
        A, B, and C 52.9938 44.081–78.656 52.6201 44.0807–77.0595 51.413 44.0802–72.6384
        B and C 23.9449 12.055–42.3612 23.1098 10.0302–41.162 20.571 8.7883–38.149
        A 45.151 44.08–47.9311 45.1336 44.08–47.8964 45.119 44.08–48.0281
        B 15.6571 8.8518–25.9166 15.1134 8.3088–24.9999 13.5672 8.1754–23.0218
        C 13.6085 8.2093–21.2408 13.3621 7.8461–20.9611 12.7738 7.522–21.2622
a

The adopted model is shaded gray.