Table 1.

Pathway Express analysis of the host response to MDV infection in the spleen

Rank	Pathway name	Impact factor	No. of input genes/no. of pathway genes	Corrected P value
1	Leukocyte transendothelial migration	69.707	10/119	3.77E−29
2	Cell adhesion molecules	46.582	15/134	2.80E−19
3	Adherens junction	24.326	3/78	6.90E−10
4	Cytokine-cytokine receptor interaction	12.714	22/263	4.13E−05
5	Antigen processing and presentation	10.45	8/89	3.31E−04
6	Complement and coagulation cascades	10.161	10/69	4.31E−04
7	Systemic lupus erythematosus	8.129	8/144	0.002691804
8	Jak-STAT signaling pathway	8.075	15/155	0.002824351
9	Toll-like receptor signaling pathway	6.922	11/102	0.007809953
10	Graft-vs-host disease	6.241	3/42	0.014104792
11	Type II diabetes mellitus	5.744	4/45	0.021593849
12	Long-term depression	5.653	8/75	0.023331938
13	Extracellular matrix-receptor interaction	5.197	10/84	0.034288862
14	Epithelial cell signaling in Helicobacter pylori infection	4.898	9/68	0.044007875
15	Axon guidance	4.631	13/129	0.054874147
16	Apoptosis	4.538	8/89	0.059227662
17	Natural killer cell-mediated cytotoxicity	4.525	6/135	0.059861797
18	p53 signaling pathway	4.279	7/69	0.073148525
19	Transcription growth factor β signaling pathway	4.171	4/87	0.079823773
20	Allograft rejection	4.1	2/38	0.084520645
21	Tight junction	3.98	9/135	0.093054484
22	ABC transporters	3.825	5/44	0.105273951
23	Type I diabetes mellitus	3.79	2/44	0.108232933
24	Gap junction	3.507	7/96	0.135150237
25	Long-term potentiation	3.495	3/73	0.136417624
26	PPAR signaling pathway	3.486	7/70	0.137375316
27	Basal cell carcinoma	3.456	1/55	0.140612346
28	Pancreatic cancer	3.306	3/72	0.157868858
29	Neuroactive ligand-receptor interaction	3.174	11/256	0.174623126
30	Proteasome	2.969	1/48	0.203826563
31	Amyotrophic lateral sclerosis	2.891	4/56	0.216030904
32	Vibrio cholerae infection	2.775	6/62	0.235369275
33	Pathogenic Escherichia coli infection	2.737	4/54	0.242024371