Table 1.
Traditional neutralization activities of anti-M and anti-H IgA and IgG MAbsa
MAb | Specificity | 15 μg/ml MAb |
30 μg/ml MAb |
||
---|---|---|---|---|---|
Virus titer (PFU/well) | % Reduction of virusb | Virus titer (PFU/well) | % Reduction of virusb | ||
5H7-IgA | Anti-M | 34.00 ± 0.58 | 0.00 | 35.00 ± 2.31 | 0.00 |
5H7-IgG | Anti-M | 32.00 ± 0.58d | 4.48 | 36.50 ± 0.87 | 0.00 |
16CD11-IgA | Anti-H | 7.50 ± 0.29c | 77.61 | 3.00 ± 0.58c | 91.04 |
16CD11-IgG | Anti-H | 14.50 ± 0.87c | 56.72 | 13.00 ± 0.58c | 61.19 |
Irrelevant IgA | Anti-HIV gp41 | 30.50 ± 1.44d | 8.96 | 31.00 ± 1.15d | 7.46 |
No MAb | 33.50 ± 0.87 | 0.00 | 33.50 ± 0.87 | 0.00 |
Experiments were repeated on at least two occasions with similar results. The results of a representative experiment are shown. The data are means ± standard errors of the mean (SEM) (n = 3).
Compared to no-antibody control.
Mean virus titers were significantly lower (P ≤ 0.0001) than those from cells exposed to no antibody.
Mean virus titers were not significantly lower (P ≥ 0.05) than those from cells exposed to no antibody.