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. 2011 Nov;85(21):11361–11371. doi: 10.1128/JVI.05046-11

Fig. 1.

Fig. 1.

Human and chimpanzee Apobec3DE restrict retrotransposons. Human and chimpanzee Apobec3DE were expressed in retrotransposition assays to determine their antiviral activity. Retrotransposition activity is normalized to 100% in the absence of Apobec3 (none). (A) Western blot analysis of protein levels of human Apobec3G (hA3G), human Apobec3A (hA3A), human Apobec3DE (hA3DE), and chimpanzee Apobec3DE (cA3DE) during transient transfection. (B) Retrotransposition of MusD. Human Apobec3G was used as a positive control. (C) Retrotransposition of the prototypic Alu element. Human Apobec3A was used as a positive control. (D) Retrotransposition of LINE-1. Human Apobec3G was used as a positive control. Experiments were performed at least 3 times, and results from one representative experiment are shown. Error bars represent the standard deviation of triplicate transfections within one experiment.