Fig. 5.
Antibody response against H5N1 virus in ducks inoculated with recombinant DEVs. Groups of ducks were inoculated intramuscularly with two doses of 105 PFU of rDEV-ul41-HA (A and B) (n = 12), rDEV-us78-HA (C and D) (n = 12) at a 3-week interval, or one dose of 106 PFU of rDEV-us78HA (E and F) (n = 6). Sera were collected from ducks weekly for HI antibody (A, C, and E) and NT antibody (B, D, and F) detection. The sera of ducks (n = 10) that were inoculated with 105 PFU of DEV also were included for comparison in panels C and D. The data for week 0 represent the pretest values. The dashed lines in A, C, and E show the limits of detection, while the dashed lines in B, D, and F show the detection limits for a positive response.