Fig. 3.

Localization of residues identified in CDV-H that control functional interaction with KeR. Shown are surface representations of the CDV-H structural model in the same orientation as in Fig. 1D. (A) Red, residues in CDV-H that contact canine SLAM based on homology modeling with MeV-H and human SLAM (11). (B) Blue, residues in CDV-H mutation of which completely inhibits KeR-dependent fusion activity; cyan, residues in CDV-H mutation of which partially inhibits KeR-dependent fusion activity; red, residues in CDV-H that contact canine SLAM based on homology modeling with MeV-H and human SLAM (11). The recessed groove is also indicated (dashed red line).