Fig. 6.
Inhibition of HCV infection by GRFTWT is genotype independent. HCVpp of different genotypes (genotypes 1a to 6) were preincubated with GRFTWT (1 μg/ml) or without GRFTWT and then transferred to Huh-7 cells. Intracellular firefly luciferase signal was measured and normalized to untreated cultures. GRFTWT had no effect on the infectivity of particle pseudotypes with VSV and RD114 envelope proteins. Experiments were performed three times, and all conditions were tested in duplicate. Error bars represent the standard errors of the means.