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. 2011 Nov;55(11):5150–5154. doi: 10.1128/AAC.00686-11

Table 2.

Wild-type (WT) MIC distributions of amphotericin B for six Aspergillus spp. from eight laboratories, obtained using CLSI M38-A2 and EUCAST microdilution methods

Species No. of isolates tested by CLSI/EUCAST methoda
Total With MIC (μg/ml) of:
≤0.03 0.06 0.125 0.25 0.5 1.0 2.0 4.0 8.0 16 32
A. fumigatus 3,988/833 13/0 56/5 323/73 600/447b 1,389b/245 1,382/53 214/7 9/1 2/1 0/1 0/0
A. flavus 793/194 7/0 3/0 8/1 63/11 141/72 363b/76b 187/27 19/6 2/1 0/0 0/0
A. nidulans 184/69 0/0 1/0 2/1 9/5 23/22 68b/21b 70/12 9/4 2/1 0/1 0/2
A. niger 673/140 2/0 43/5 38/55 122/71b 252b/9 194/0 12/0 0/0 0/0 0/0 0/0
A. terreus 545/266 0/0 0/0 3/0 10/35 21/37 109/104b 297b/86 84/22 20/9 1/4 0/1
A. versicolor 135/22 1/0 1/0 4/1 3/2 13/2 76b/9b 26/3 10/1 1/0 0/0 0/0
a

Number of isolates tested by the CLSI and EUCAST broth microdilution methods (8, 30), including CLSI aggregated data from eight laboratories and EUCAST data from a single laboratory.

b

MIC most frequently obtained by each broth microdilution method.