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Inhibition of S. aureus metabolic pathways by compounds 1 and 2
| Test agent | IC50 (μg/ml) |
|
|---|---|---|
| Protein synthesis (mean ± SD) | Fatty acid, DNA, RNA, and cell wall synthesis | |
| Compound 1 | 0.06 ± 0.02 | >32 |
| Compound 2 | 0.05 ± 0.01 | >32 |
| Erythromycin | 0.62 ± 0.1 | >128 |
