Fig. 4.

Effects of peramivir and oseltamivir phosphate treatment on nasal inflammatory cell count, protein concentration, and weight change of ferrets infected with B/Kadoma/1/2005. The means ± SDs of 4 ferrets (6 ferrets for the untreated control group) are shown in the graphs. P values are calculated by comparison with the control group. (A) Protein concentration in nasal washes (*, P < 0.05; **, P < 0.01); (B) total number of inflammatory cells in nasal washes (*, P < 0.01; **, P < 0.001); (C) body weight change. Percent body weight was calculated on the basis of the body weight measured on the indicated days compared with the weight before inoculation with virus (*, P < 0.05).