Table 3.
Multivariate analysis of the association of amino acid changes from the reference sequence HXB2 in the single variable regions of gp120 with early or late R5 strains
Region | Amino acid changes | P value | Odds ratio | 95% CI |
---|---|---|---|---|
V1 | N136L | 0.014 | 0.02 | 0.00–0.48 |
S144 del | 0.026 | 0.07 | 0.00–0.73 | |
V2 | D187 del | 0.002 | 442.45 | 10.09–19,386.92 |
D187N | 0.034 | 22.88 | 1.27–410.35 | |
V3 | R306G | 0.004 | 0.01 | 0.00–0.25 |
V4 | S398Q | 0.043 | 25.10 | 1.10–570.33 |
V5 | E464N | 0.015 | 34.27 | 2.00–586.66 |