Table 1.
MICs of β-lactams for S. marcescens and E. coli strains
| β-Lactama | MIC (μg/ml) |
||||
|---|---|---|---|---|---|
| S. marcescens M1 and M4 | E. coli TOP10(pOXA-48) | S. marcescens CIP81(pOXA-48) | E. coli TOP10 | S. marcescens CIP81 | |
| Amoxicillin | >256 | >256 | >256 | 4 | >256 |
| Amoxicillin + CLA | >256 | >256 | >256 | 4 | >256 |
| Ticarcillin | >256 | >256 | >256 | 4 | 4 |
| Ticarcillin + CLA | >256 | >256 | >256 | 4 | 4 |
| Piperacillin | 64 | 64 | 64 | 2 | 2 |
| Piperacillin + TZB | 64 | 64 | 64 | 2 | 2 |
| Cephalothin | >256 | 8 | >256 | 4 | >256 |
| Ceftazidime | 0.25 | 0.12 | 0.12 | 0.12 | 0.12 |
| Cefotaxime | 2 | 0.25 | 1 | 0.06 | 0.25 |
| Aztreonam | 0.25 | 0.06 | 0.06 | 0.06 | 0.06 |
| Cefepime | 4 | 0.25 | 1 | 0.06 | 0.12 |
| Imipenem | 8 | 0.5 | 1 | 0.06 | 0.25 |
| Ertapenem | >32 | 0.25 | 0.5 | 0.06 | 0.06 |
| Meropenem | 4 | 0.06 | 0.12 | 0.01 | 0.03 |
a
CLA, clavulanic acid at a fixed concentration of 4 μg/ml; TZB, tazobactam at a fixed concentration of 4 μg/ml.