Fig. 7.

Histological appearance of normal dorsal skin of mice (A), immediately after blade scratching of the skin (B), 4 days after blade scratching of the skin (C), 4 days after ctriporin treatment of S. aureus-infected skin (D), 4 days after placebo treatment of S. aureus-infected skin (E), and 4 days after no treatment of S. aureus-infected skin (F). Biopsy specimens were obtained immediately after the termination of the experiment, fixed in formalin, and embedded in paraffin. The biopsy specimens were stained with hematoxylin and eosin. Infected lesions are outlined in boxes. Numbered arrows indicate the following: 1, corneum; 2, epidermis; 3, dermis; 4, muscular layer; and 5, bacteria.