Table 2. Serum biochemicals and inflammatory factors in cirrhotic rats*.
Healthy control | CCl4 + saline | CCl4 + NaHS | CCl4 + PAG | |
(n = 6) | (n = 11) | (n = 12) | (n = 10) | |
ALT (IU/L) | 34.4±8.9 | 198.8±26.7a | 137.6±20.3a,b | 208.5±36.4a |
AST(IU/L) | 80.3±12.5 | 466.7±46.4a | 317.5±78.2a,b | 515.0±97.6a,b |
HA (µg/L) | 113.5±20.1 | 482.6±51.4a | 296.3±32.1a,b | 549.0±47.3a,b |
Albumin (g/L) | 472.5±43.8 | 314±51.6a | 443.7±80.5a,b | 294.3±32.8a |
TNF-α (ng/L) | 43.9±6.8 | 143.5±21.4a | 109.3±22.6a,b | 176.3±28.5a,b |
IL-1β(ng/L) | 20.3±5.0 | 75.4±10.2a | 50.6±9.8a,b | 80.2±17.4a |
IL-6 (ng/L) | 87.0±15.9 | 297.1±55.4a | 216.4±42.1a,b | 320.6±51.4a |
ICAM-1(ng/L) | 69.2±8.7 | 180.8±19.7a | 153.6±22.8a,b | 207.2±31.3a,b |
*Data are expressed as means ± SD, and statistical analysis was performed by one-way ANOVA analysis followed by the post-hoc Dunnett's test.
Significant difference (P<0.05) from healthy controls.
Significant difference (P<0.05) from CCl4+saline-treated rats.