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. 2011 Sep 26;42(1):103. doi: 10.1186/1297-9716-42-103

Figure 1.

Figure 1

Cloning of bovine PD-L1. A: Nucleotide and deduced amino acid sequences of bovine PD-L1 cDNA. Bovine PD-L1 cDNA has an open reading frame extending from positions 61 to 930 and encodes for a 290 aa polypeptide. The putative signal peptide and polyadenylation signal are underlined with dotted and solid lines, respectively. B: Alignment of deduced amino acid sequences of vertebrate PD-L1. Bold line indicates the transmembrane domain (238-259) of bovine PD-L1. C: Phylogenetic tree constructed from nucleotide sequences of vertebrate PD-L1 by the Mega 4 software. The bootstrap values supporting a particular cluster are shown within the node. Numbers indicate the bootstrap percentage (100 replicates). The scale indicates the divergence time. Clusters were identified based on their Order.