Figure 4.
Correlation between markers of disease progression and PD-L1 expression in BLV-infected cattle. Positive correlation between the leukocyte number (A: n = 36; AL: 8 PL: 20 EBL: 8), provirus load (B: n = 41; AL: 12 PL: 20 EBL: 9) or virus titer (C: n = 39; AL: 12 PL: 19 EBL: 8) and the percentages of PD-L1+ cells in PBMC corresponding to Figure 3b. The provirus load and virus titer were determined using quantitative real-time PCR and syncytium formation assay, respectively. Correlation statistics were analyzed using the Spearman correlation.