Table 1.
Histopathological scores of the distal colons of mice
| Control | CTC | CR | CTC+CR | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cat/Day | 3 | 8 | 14 | 21 | 3 | 8 | 14 | 21 | 3 | 8 | 14 | 21 | 3 | 8 | 14 | 21 |
| EHa | 0b | 0 | 0 | 0-1 | 0-1 | 0-1 | 0-1 | 0 | 0-1 | 1-2 | 2-4 | 1-2 | 0 | 2 | 1-3 | 0-1 |
| CH | 0 | 0 | 0 | 0 | 0-1 | 0 | 0-1 | 0 | 0-1 | 2 | 2-4 | 1-2 | 0-1 | 2-3 | 1-3 | 0-2 |
| EI | 0 | 0 | 0 | 0 | 0-1 | 0 | 0 | 0 | 0 | 3-4 | 2-3 | 0-2 | 0 | 3 | 0-4 | 0-2 |
| II | 0 | 0-1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2-4 | 3-4 | 1-4 | 0 | 3-4 | 1-4 | 0-2 |
| MA | 0 | 0-1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2-3 | 3 | 1 | 0-1 | 2-3 | 1-3 | 1-2 |
| GC | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1-2 | 2-3 | 0-1 | 0 | 1-2 | 0-3 | 0 |
| Total | 0 | 0-1 | 0 | 0-1 | 0-2 | 0-2 | 0-2 | 0-1 | 0-1 | 13-15 | 16-20 | 4-12 | 0-1 | 14-16 | 4-20 | 1-9 |
aPathology categories (Cat): EH, epithelial hyperplasia; CH, crypt height; EI, epithelial injury; II, inflammatory infiltrates; MA, mitotic activity; GC, globlet cell depletion. Total score corresponds to the sum of scores of all categories.
bRange of scores were: 0 to 4 for EH, CH, EI, II; 0 to 3 for MA, GC; 0 to 22 for Total.