Table 2.

Taxonomic distribution of homologues of major APC/C targets in major lineages of eukaryotes.

	Core complex				Loading complex		Cohesion establishment	Maintenance		Dissolution
	Smc1	Smc3	Scc1	Scc3	Scc2	Scc4	Eco1	Pds5	Wpl1/Rad61	Separase	Securin
Choanoflagellata	100	100	100	100	100		Half	100	Half	100
Metazoa	>50	>50	>50	100	100	100	100	100	100	>50	< 50
Capsaspora	100	100	100	100	100	100	100	100	100	100
Fungi/Dikarya	100	100	100	100	100	>50	>50	100	100	100	< 50
Fungi/Microsporidia	>50	>50		>50						>50
Fungi/Chytridiomycota	100	100	100	100	100	50	100	100	100	100
Apusozoa	100	100	100	100	100		100			100
Amoebozoa	100	100	100	>50	>50		>50	>50		100
Excavata	100	100	>50	>50	< 50		>50	>50		100
Alveolata/Ciliata	100	< 50	< 50							>50
Alveolata/Apicomplexa	100	>50	< 50	>50						>50
Heterokonta	100	>50	>50	>50	>50		>50	>50		>50
Plantae/Viridiplantae	100	100	100	100	>50	>50	>50	100	>50	>50
Plantae/Rhodophyta	100	100	100	100	>50		100	>50		100
Haptophyta	100	100	100	100	100		100	100		100

100, > 50, and < 50 indicate that at least one orthologue has been detected respectively in all, at least 50%, and less than 50% of the studied genomes for a given lineage.