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Frequency of vaccine-related AEs in single dose groups. For each dose of vaccine given (n = 15), the mean number of AE reports recorded within one month of each vaccine dose is shown by (a) AE site or (b) severity of AE. Multiple reports of the same AE for the same volunteer have only been counted once. Vaccine doses were 1 × 108, 2 × 108 or 5 × 108 pfu for low, med and hi groups respectively.
