Fig. 3.

Frequency and duration of vaccine-related AEs in prime-boost groups. For each dose of vaccine given (n = 68), the mean number of AE reports recorded within one month of each vaccine dose is shown by (a) AE site or (b) severity of AE. (c) Shows moderate AEs only and (d) the mean duration in days of related AEs beginning within one month of vaccination. Multiple reports of the same AE for the same volunteer and vaccine dose have only been counted once, but durations have been summed. Vaccine doses were 1 × 10⁸ for vaccine 1 (prime) and 2 × 10⁸ for vaccines 2 and 3 (boosts) for both groups.