Table 2.

Changes in depression and hot flash scores from baseline to end point

variable change from baseline to end of study	n*	Mean Pre- Treatment Score	Mean Post- Treatment Score	Mean Change Score	Standard Deviation of Mean Change Score	Median of the Change Score	IQR of the Change Score	pvalue
MADRS	20	24.2 ± 3.9	10.7 ± 8.5	13.5	7.9	13.5	7.0	<0.0001*
Hot Flash Scores: 24-hour score	15	9.0 ± 10.3	2.5 ± 4.0	5.1	9.70	2.1	5.4	0.02*
Daytime hot flash score	15	4.3 ± 4.8	1.8 ± 3.6	2.0	5.0	0.9	2.9	0.05*
Nighttime hot flash score	15	4.6 ± 5.5	0.7 ± 0.8	3.2	4.9	1.1	3.1	0.002*
HFRDIS	15	36.9 ± 27.7	14.1 ± 24.2	22.9	27.5	20.0	44.0	0.37

^*indicates significant change from baseline to endpoint (with alpha ≤ 0.05)

N=20, number of participants who started omega-3 fatty acids after the one-week placebo lead in N=15, number of participants who had hot flashes at baseline and could be included in the hot flash analyses