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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Bioorg Med Chem. 2011 Aug 4;19(18):5480–5489. doi: 10.1016/j.bmc.2011.07.046

Scheme I.

Scheme I

Synthesis of 2maleimido-paclitaxel was prepared via coupling paclitaxel with 3-maleimidopropionic acid (compound 1).