Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of APPD. Reagents and conditions: (a) OsO4, NMO, H2O/acetone (5:1 v/v), 50 °C; (b) 2,2-dimethyloxypropane/TyOH; (c) LiAlH4, THF, 80 °C; (d) H2, Pt/C, MeOH; (e) 4-cyanobenzene-1-sulfonyl chloride, Et3N, MeCN; (f) H2, Pt/C, MeOH, 10% conc. HCl.
