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. 2011 Sep 19;38(10):5490–5499. doi: 10.1118/1.3633935

Table 2.

The skin dose mapping program determines the amount of skin area receiving doses within the four ranges where effects can be expected.

    Approximate Time of Onset of Effects
Single-Site Acute Skin-dose Range (Gy) NCI Skin Reaction Grade Prompt Early Midterm Long Term
0–2 NA No observable effects expected No observable effects expected No observable effects expected No observable effects expected
2–5 1 Transient erythema Epilation Recovery form hair loss No observable effects expected
5–10 1–2 Transient erythema Erythema, epilation Recovery; at higher doses, prolonged erythema, permanent partial epilation Recovery; at higher doses, dermal atrophy or induration
10–15 2–3 Transient erythema; Erythema, epilation; possible dry or moist desquamation; recovery form desquamation Prolonged erythema; permanent epilation Telangiectasia; dermal atrophy or induration; skin likely to be weak
>15 3–4 Transient erythema; after very high doses, edema and acute ulceration; long term surgical intervention likely to be required Erythema, epilation moist desquamation Dermal atrophy secondary ulceration due to failure of moist desquamation to heal; surgical intervention likely to be required: at higher doses, dermal necrosis, surgical intervention likely to be required Telangiectasia; dermal atrophy or induration; possible late skin breakdown; wound might be persistent and progess into a deeper lesion; surgical intervention likely to be required