Figure 3. Contributions of trafficking molecules to CD8+ T cell extravasation.
Determination of rolling fractions and sticking fractions by intravital microscopy (A) or short-term (1 hour) homing (B) of fluorescently tagged TK1 CD8+ T cells in CT26 tumors after treatment with function-blocking reagents (i.e., antibodies or PTX). Data are pooled from 3 independent experiments (A) or are representative of at least 3 independent experiments (B). *P < 0.001, #P < 0.05 versus control antibody.