Figure 3. Effect of cytokines on MDM killing of BCG in 10% O₂.

(A and B) MDMs differentiated in 10% O₂ without added cytokines for 14 days were treated or not with IFN-γ (5 ng/ml) or other cytokines on day 14 and infected with BCG (MOI of 0.1) on day 16. CFU were measured 21 days after infection. (A) Number of CFU for each donor, pooled results, and input on day 0. (B) Percentage of control of growth compared with cells treated with PBS instead of cytokines. Experiments in A and B are representative of 7 independent experiments with cells from 2 donors.