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. 2011 Sep 1;121(10):3954–3964. doi: 10.1172/JCI57362

Figure 2. ASCs in lungs of influenza virus–infected BLIMP-1–YFP mice are sensitive to irradiation.

Figure 2

(A) Influenza virus PR8–infected BLIMP-1–YFP mice (n = 3–9 mice/group) were subjected to whole-body irradiation (7.5 Gy) at 6 days, 3–4 weeks, or 4 months p.i. and analyzed 10 days later together with non-irradiated controls. (B) Total YFP+ ASCs in lungs, spleen, and BM were determined by flow cytometry. (C) PR8-specific ASCs were determined by ELISPOT. (D) PR8-specific IgG Ab titers in sera from control and irradiated mice were measured by ELISA. All data with mean ± SEM represent at least 2 independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.