Figure 6. Ubiquitinated proteins accumulate in JASL cells.

(A) Expression of ubiquitin in transformed B cells from healthy control, 1-1M, and 1-3PT, evaluated by Western blotting with anti-ubiquitin and β-actin mAbs. Data are representative of 5 experiments. (B–F) Skin sections of a healthy control (B and C) and 2-2B (D–F) stained with anti-ubiquitin mAb together with hematoxylin. Original magnification, ×20 (B and D); ×40 (C and E). The boxed region in E is shown enlarged in F. Histological data are representative of 4 independent staining experiments using a biopsy sample from each patient. Scale bars: 100 μm (B and D); 50 μm (C and E); 10 μm (F).