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. Author manuscript; available in PMC: 2012 Nov 18.
Published in final edited form as: Toxicology. 2011 Aug 16;289(2-3):141–150. doi: 10.1016/j.tox.2011.08.009

Table 5.

Statistically Significant Clinical Chemistry Findings in Dogs Receiving CP-31398

Sex Day Parameter(s) increased in Groups Exposed to CP- 31398 Group(s) Parameter(s) Decreased in Groups Exposed to CP-31398 Group(s)
Male 4 None -- Pi Mid, High
Male 8 ALT High Pi
ALP		 Low, Mid
Mid, High
Male 15 None -- Pi
Glucose		 Low, Mid, High
Mid, High
Male 22 None -- None --
Male 29 BUN/creatinine ratio High None --
Male 43 BUN High Pi
A/G ratio		 Mid
High
Female 4 ALT High None --
Female 8 K+
ALT		 High
High		 ALP
Glucose		 Low, Mid, High
Mid, High
Female 15 K+ Mid, High Pi Mid, High
Female 22 Cl-
Globulin		 High
Low, Mid		 Albumin
A/G ratio
Glucose		 High
Low, Mid
Low, Mid, High
Female 29 Globulin
Triglycerides		 Low, High
High		 A/G ratio Low, High
Female 43 None -- None --