Table 2.
Examples of the use of gold nanoparticles in clinical practice
| Type of Gold Nanoparticle |
Nanoparticle Size (nm) |
Role | Disease State |
Sponser/Lab |
|---|---|---|---|---|
| Nanosphere | 13 | siRNA delivery | Unspecified | Mirkin |
| Nanorod | 10 × 40 | Photothermal ablation; CT contrast and thermal imaging | Unspecified | Bhatia |
| Gold-silica Nanosphere | 60/140 | Raman Imaging | Colon Cancer | Gambhir |
| Gold Nanoshell (Aurolase™) | 150 | Photothermal therapy | Head and Neck cancer | NanoSpectra NCT00848042 |
| Gold Colloidal Nanosphere (Aurimune™) | 27 | Stimulate immune response to tumor growth | Solid Tumors | NCI NCT00436410 |