Fig. 1.

Immunohistochemistry for 5-bromo-2'-deoxyuridine (BrdU) in the hippocampal dentate gyrus (DG) of the vehicle- (A, B) and earthworm extract (EE)-treated (C, D) groups. BrdU⁺ cells (arrows) in the DG of the EE-treated group were lower than those in the vehicle-treated group. GCL, granule cell layer; ML, molecular layer; PL, polymorphic layer; SGZ, subgranular layer. Scale bar=100 µm. (E) Mean number of BrdU⁺ cells per section in the vehicle- and EE-treated groups (n=7/group; ^*P<0.05, significantly different from the vehicle-treated group).