Table 4.
Secondary progressive MS. The patients were classified according to the relationship of CSF and blood NfH levels. If the concentration was higher in the CSF compared to the blood, this was indicated by “C > S” and “S ≥ C” otherwise. The data is presented for each of the two NfH phosphoforms quantified (NfHSMI34 and NfHSMI35). ⋆ P < .05.
| Characteristic | NfHSMI35 | NfHSMI34 | ||
|---|---|---|---|---|
| C > S | S ≥ C | C > S | S ≥ C | |
| Number | 15 | 3 | 11 | 7 |
| Age | 45 (29–55) | 57 (32–65) | 49 (32–65) | 44 (29–50) |
| Gender (female : male) | 6 : 9 | 3 : 0 | 7 : 4 | 2 : 5 |
| Disease duration (years) | 16 (6–28) | 22 (15–24) | 19 (6–28) | 16 (7–22) |
| EDSS | 5 (1–8) | 7 (6–8) | 6 (3–8) | 3 (1–7) |
| ΔEDSS | 0 (−1–3) | 0 (−2–0) | 0 (−1.5–1.5) | 2 (−1–3)⋆ |