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. Author manuscript; available in PMC: 2012 Oct 20.
Published in final edited form as: FEBS Lett. 2011 Sep 7;585(20):3245–3249. doi: 10.1016/j.febslet.2011.08.050

Table 1.

IC50 (nM) Values for inhibitors*

Inhibitor Chk2 Chk1 RSK2
PV1322 12.67±11.90 34000 >100000
PV1019 0.16±0.03 8100 39000
PV1352 0.17±0.01 36000** >100000
PV1162 0.29±0.14 59000** >100000
*

Tabulated data is from head-to-head testing using a single batches of each enzyme. Chk2 values are the mean±S.D. from at least duplicate experiments. Chk1 and RSK2 determinations were single assays except as indicated of PV1352 and PV1162.

**

Archival assay data (mean of duplicate assays).