Table 5. Blood group stratified by alcohol consumption and mutation status.
| Blood Group | A | AB | B | O | |
|---|---|---|---|---|---|
| All Samples | 1130 | 465 (41.2%) | 57 (5.0%) | 120 (10.6%) | 488 (43.2%) |
| Number | Number (Percent) | ||||
| Controls (all) | 631 | 269 (42.6%) | 35 (5.5%) | 62 (9.8%) | 265 (42.0%) |
| Unrelated controls | 455 | 192 (42.2%) | 23 (5.1%) | 41 (9.0%) | 199 (43.7%) |
| Related Controls | 176 | 77(43.8%) | 12 (6.8%) | 21 (11.9%) | 66 (37.5%) |
| Chronic Pancreatitis Patients Only | |||||
| Number | Number (Percent) | ||||
| Chronic pancreatitis (CP) | 499 | 196 (39.3%) | 22 (4.4%) | 58 (11.6%) | 223 (44.7%) |
| Idiopathic CP | 145 | 64 (44.1%) | 5 (3.4%) | 15 (10.3%) | 61 (42.1%) |
| Alcohol=-related/heavy drinking subgroups | Number | Number (Percent) | |||
| Alcohol-related (per physician's diagnosis)† | 219 | 76 (34.7%) | 10 (4.6%) | 25 (11.4%) | 108 (49.3%) |
| Not alcohol-related | 280 | 120 (42.9%) | 12 (4.3%) | 33 (11.8%) | 115 (41.1%) |
| Very heavy drinkers¥ with CP | 125 | 45 (36.0%) | 6 (4.8%) | 14 (11.2%) | 60 (48.0%) |
| Not very heavy drinkers with CP | 374 | 151 (40.4%) | 16 (4.3%) | 44 (11.8%) | 163 (43.6%) |
| Predisposing mutation status | |||||
| Mutation carriers with CP* | 151 | 64 (42.4%) | 8 (5.3%) | 21 (13.9%) | 58 (38.4%) |
| Non-mutation carriers with CP | 348 | 132 (37.9%) | 14 (4.0%) | 37 (10.6%) | 165 (47.4%) |
Alcoholism/heavy drinking subgroups
†
Alcohol-related =either the singular or a contributing etiology, as per physician reporting
¥
Very heavy drinkers = ≥5 drinks per day or ≥35 drinks per week for men or women
*
Mutations in any of the following genes: PRSS1 (cationic trypsinogen), CFTR (cystic fibrosis transmembrane receptor) and SPINK1 (serine protease Kazal type I)