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. 2011 Oct 13;7(10):e1002144. doi: 10.1371/journal.pcbi.1002144

Figure 3. Selection of HLA–B allele parameters.

Figure 3

The horizontal axis indicates the set of parameters that were allowed to vary between alleles. The vertical axis quantifies the Bayesian information criterion (BIC) of the best parameter values for a given set of allele parameters. BIC penalizes deviations of the model simulation from the experimental data, whilst also penalizing models with more variable parameters, implying that low BIC values correspond to more representative models. The best parameter values for a given set of allele parameters were inferred using the Filzbach MCMC software (see Methods).