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. Author manuscript; available in PMC: 2012 Oct 14.
Published in final edited form as: Biochem Biophys Res Commun. 2011 Sep 17;414(1):170–174. doi: 10.1016/j.bbrc.2011.09.050

Fig. 3.

Fig. 3

Inhibition of AMPK and SIRT negates Leptin’s effect on Aβ(1–40) in RA-SY5Y. Cells were treated overnight with or without Leptin (500 ng/mL) in the presence or absence of nicotinamide (5 mM) or compound C (20 μM), and culture media collected for determination of Aβ(1–40) levels by ELISA. Results were normalized to total protein and presented as a percentage relative to vehicle control, n=3.

*p<0.05 vs. no Leptin