. Author manuscript; available in PMC: 2012 Oct 30.

Published in final edited form as: J Control Release. 2011 Jul 19;155(2):272–281. doi: 10.1016/j.jconrel.2011.07.018

Table 1.

Physicochemical characterization of DOX-loaded PEG^5k -CAs₈ and PEG^2k -CA₄ micelles

Telodendrimers	DOX/polymer (w/w, %)	Particle size (nm)^a	DL (%)	EE (%)	DOX concentration in micelles^b(mg/ml)
PEG^5k-CA₈	0	16 ± 3	N/A	N/A	N/A
	5	15 ± 5	4.6	91	0.91
	10	17 ± 7^*	7.8	78	1.56
	15	20 ± 9^*	8.2	55	1.65
PEG^2k-CA₄	0	10 ± 2	N/A	N/A	N/A
	5	10 ± 3	4.8	99	0.99
	10	10 ± 4	9.7	97	1.94
	15	12 ± 5	14.8	98	2.94
	20	18 ± 6^*	13.2	66	2.64
	25	22 ± 8^*	7.3	30	1.5

The sample was filtered through 0.22 μM filter due to the precipitation.

Data represent the mean ± standard deviation (n ± 3).

The telodendrimer concentration was kept at 20 mg/ml.