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. 2011 Aug 23;286(42):36852–36863. doi: 10.1074/jbc.M111.219931

FIGURE 3.

FIGURE 3.

Increase of invA transcription and expression levels of invAcom revertant and wild type (WT) of L. interrogans strain Lai during infection. A, mRNA levels of the invAcom revertant and wild type during infection of HEK293 and THP-1 cells for the indicated times. mRNA levels of wild-type L. interrogans strain Lai in EMJH and PRMI 1640 media served as controls. * and #: p < 0.05 versus leptospires in both EMJH and RPMI 1640 media, respectively. B, InvA protein expression levels of the invAcom revertant and wild type during infection of HEK293 and THP-1 cells for the indicated times. Membrane lipoprotein LipL41 expression levels of wild-type L. interrogans strain Lai served as controls. M, protein marker (BioColor); N, blank controls.