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Single deficiencies of TLR2, TLR9, or TLR5 do not display decreased bacterial resistance during E. coli peritonitis. Mice were challenged intraperitoneally with 104 pathogenic E. coli and sacrificed after 20 h. Local and systemic outgrowth of bacteria were evaluated as described under “Experimental Procedures.” Data are means ± S.E. (error bars) (n = 8/group). The asterisks indicate significant differences with WT. *, p ≤ 0.05; **, p ≤ 0.005.
