The alignment of the top 5 PDB hits obtained from Blastp and top 5 hits obtained by Dali. The circle highlights the difference in the substrate binding loop between BphBB-356 (in black) and other PDB structures (light color). PDB code 1BDB and BphBB-356 are shown in black color, and other structures are shown in light colors. These PDB codes are: 2HQ1, 3OEC, 3PKO, 2UVD, 2PNF, 2WSB, 1YDE, 2WDZ, 1HDC, and 1NFR.