FIGURE 8.

A, the superimposed docked structure of cis-(2R,3S)-dihydroxy-1-phenyl-cyclohexa-4,6-diene, 2,3-dihydro-2,3-dihydroxy-2,4,4′-trichlorobiphenyl, 2′,3′-dihydro-2′,3′-dihydroxy-2,6-dichlorobiphenyl, 3′,4′-dihydro-3′,4′-dihydroxy-2,6-dichlorobiphenyl, 5,6-dihydro-5,6-dihydroxy-3,3′dichlorobiphenyl, and product 2,3-dihydroxybiphenyl with NAD⁺ in stick model. B, the aligned substrates in surface representation of protein highlighting the cavity large enough to accommodate different substrates with different orientations of their distal rings.