Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Regulation of PI 3-kinase-dependent genes by MITF, USF1, and FoxO in Rat1 cells. ChiPs were performed with anti-MITF (A), anti-USF1 (B), and anti-FoxO1 and anti-FoxO3a antibodies (C) in proliferating Rat-1 cells treated with either DMSO or PI-103 for 1 h. Data are the mean ± S.E. of 3 samples. Binding of MITF, USF1, and FoxO3a upstream of ATROGIN-1, CCNG2, and TXNIP was significantly higher than MyoG controls after PI-103 treatment (p < 0.05).
