Responses of Pla2g1b+/+ and Pla2g1b−/− mice to hypercaloric diet feeding. The Pla2g1b+/+ mice (filled bars) and Pla2g1b−/− mice (open bars) were placed on hypercaloric diets for the time indicated. Body weights (A), fasting plasma triglyceride (B), and cholesterol (C) levels were taken. Results shown are mean ± SE from six Pla2g1b+/+ and five Pla2g1b−/− mice (for weeks 0 and 3 time points) and seven mice in each group at the week 10 time point. *P ≤0.05, **P ≤ 0.01, ***P ≤ 0.001 versus Pla2g1b+/+ mice; and #P ≤ 0.05, ##P ≤ 0.01, and ###P ≤ 0.001 versus week 0 data of the respective genotype.