Table 3. Brain Regions Exhibiting Change in Activation During Correct “No-Go” Trials of the Go/No-Go Task.
| Brain Region | Vol (μl) | x | y | z | p1 | ADHD | (SD) | CTRL | (SD) | df | t | p2 | d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No-Go > 0*** | |||||||||||||
| Frontal | |||||||||||||
| (1) R FEF (BA 6) | 1,888 | 34 | 0 | 48 | 0.001* | 0.23 | (0.22) | 0.71 | (0.19) | 21 | 5.72 | <0.01* | 2.34 |
| (2) R Pre-SMA (BA 6) | 1,692 | 6 | 9 | 47 | 0.001* | 0.46 | (0.50) | 0.83 | (0.32) | 18 | 2.16 | 0.04* | 0.88 |
| (3) L Precentral Gyrus (BA 4) | 858 | -41 | -2 | 31 | 0.02* | 0.42 | (0.41) | 0.84 | (0.39) | 21 | 2.57 | 0.02* | 1.05 |
| (4) R IFG† (BA 44) | 1,340 | 46 | 5 | 28 | 0.001* | 0.64 | (0.28) | 0.80 | (0.33) | 21 | 1.28 | 0.21 | 0.52 |
| (5) R Anterior Insula (BA 13) | 1,130 | 34 | 14 | 2 | 0.003* | 0.51 | (0.24) | 0.75 | (0.36) | 19 | 1.92 | 0.07 | 0.78 |
| Parietal | |||||||||||||
| (7) R Inferior Parietal Lobe (BA 40) | 2,419 | 36 | -53 | 38 | 0.001* | 0.44 | (0.32) | 0.69 | (0.25) | 20 | 2.13 | 0.04* | 0.87 |
| (8) L Inferior Parietal Lobe (BA 40) | 1,003 | -32 | -48 | 37 | 0.01* | 0.37 | (0.32) | 0.59 | (0.18) | 17 | 2.08 | 0.05* | 0.85 |
| (9) L Precuneus (BA 39) | 509 | -27 | -69 | 34 | 0.19 | 0.34 | (0.28) | 0.70 | (0.26) | 21 | 3.26 | <0.01* | 1.33 |
| Occipital | |||||||||||||
| (11) R Inferior Occipital Gyrus (BA 18) | 470 | 30 | -89 | -5 | 0.23 | 0.58 | (0.50) | 0.56 | (0.26) | 16 | -0.12 | 0.90 | -0.05 |
| No-Go < 0*** | |||||||||||||
| Frontal | |||||||||||||
| (6) L Anterior Cingulate (BA 32) | 753 | -2 | 39 | -6 | 0.05* | -0.89 | (0.62) | -0.83 | (0.60) | 21 | 0.24 | 0.81 | 0.10 |
| (12) L Superior Frontal Gyrus (BA 9) | 602 | -10 | 52 | 22 | 0.12 | -0.81 | (0.37) | -0.80 | (0.79) | 15 | 0.04 | 0.97 | 0.02 |
| Parietal | |||||||||||||
| (10) Precuneus (BA 31) | 4,706 | 0 | -68 | 18 | 0.001* | -0.66 | (0.20) | -0.48 | (0.46) | 15 | 1.24 | 0.23 | 0.51 |
Note. Regions are labeled and numbered as in Table 2, Figure 2, and Figure 3. Coordinates and abbreviations follow the same convention as in Table 2. p1 = α per cluster as estimated by AlphaSim (i.e., corrected α). Average parameter estimates of magnitude of hemodynamic response (±SD) during correct No-Go trials are listed for each experimental group in each fROI. Summary statistics (i.e., t, p, and Cohen's d) describe the result of direct comparisons of magnitude of hemodynamic response between groups (i.e., ADHD vs. Control) within each fROI while each group performed correct No-Go trials. Positive t and d values represent ADHD < CTRL. p2 = α related to comparison of average magnitude of response within an fROI (ADHD vs Control);
p <.05;
p < .005 (uncorrected), 200 μl cluster size threshold;
p < .0005 (uncorrected), 350 μl cluster size threshold;
pars opercularis