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. Author manuscript; available in PMC: 2012 Oct 12.
Published in final edited form as: Structure. 2011 Sep 8;19(10):1413–1423. doi: 10.1016/j.str.2011.06.019

Figure 1.

Figure 1

(A) Chemical structures of tetrahydrofolate (1), folate (2), folinic acid (3), and 7-deazaguanine (4). The R group of compounds (2) and (3) correspond to the para-aminobenzoate/glutamyl moieties in THF. (B) Secondary structure of the aptamer domain of the Streptococcus mutans folT riboswitch. The regions shaded in gray were changed from the wild type sequence to facilitate transcription and crystallizability.