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. 2011 Aug 20;1(7):897–912.

Figure 1.

Figure 1

Scheme of the domain structure and main binding proteins of human ZEB1 and ZEB2. Percentages indicate identity at the amino acid level (GenBank accession numbers U12170 and AB011141, respectively). Proteins labeled in green represent coactivators, in red corepressors and in blue other transcription factors. Nt-ZFC: N-terminal zinc finger cluster. SID: Smad-interacting domain; Mid-ZFC: mid zinc finger cluster; HD: Homeodomain; CID: CtBP-interacting domain; Ct-ZFC: C-terminal zinc finger cluster. High degree of amino acid identity between ZEB1 and ZEB2 is mostly restricted to the Nt-ZFC and C-ZFC (89% and 95%, respectively), the SID (42%) and the homeodomain (46%).