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Inhibition of STICs by SKF96365 (SKF). A–C: exposure to SKF (30 μmol/l) during ANG II (10 nmol/l) stimulation inhibited STIC activity. D: example record showing the reversible inhibition of membrane current (top) and [Ca2+]CYT oscillations (bottom). E: partial inhibition of ANG II-induced vasoconstriction of isolated, perfused DVR by SKF. *P < 0.05; **P < 0.01 vs. control period.
